SCHEMBL1456355

SCHEMBL1456355

NCC1=CC=CCC1=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1601967 0.83 HTR7 (0.30)
SCHEMBL9405105 0.79
SCHEMBL1888312 0.78
SCHEMBL1122688 0.77
SCHEMBL4984798 0.77
SCHEMBL3252538 0.77
SCHEMBL6266389 0.77
SCHEMBL7684349 0.77
SCHEMBL3980860 0.77
SCHEMBL55040 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5908960-A Compounds SMITHKLINE BEECHAM CORPORATION (US) 1999-06-01 US claimed
CN-119446301-A Method for predicting reaction substrate of isowurtzitane cage compound based on machine learning 北京理工大学 2025-02-14 CN disclosed
CN-119371674-A Preparation method of donor-acceptor type metal organic framework photocatalyst and application of photocatalytic amine oxide/thioether 长沙理工大学 2025-01-28 CN disclosed
CN-116600615-B Perovskite film preparation method and solar cell device application 南开大学 2024-10-18 CN disclosed
CN-114773278-B Quinazoline compound and application thereof in antiviral 苏州大学 2024-07-30 CN disclosed
CN-114957152-B Synthesis method of benzoxazole compound 湖南第一师范学院 2023-11-17 CN disclosed
CN-114853676-B Synthesis method of 1H-imidazole compound 湖南第一师范学院 2023-11-17 CN disclosed
CN-116600615-A Perovskite film preparation method and solar cell device application 南开大学 2023-08-15 CN disclosed
US-20190210992-A1 AGONISTS THAT ENHANCE BINDING OF INTEGRIN-EXPRESSING CELLS TO INTEGRIN RECEPTORS TEXAS HEART INSTITUTE (US) 2019-07-11 US disclosed
US-10287264-B2 Agonists that enhance binding of integrin-expressing cells to integrin receptors TEXAS HEART INSTITUTE (US) 2019-05-14 US disclosed
WO-2009003669-A2 PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT 4 AZA IP NV (BE) 2009-01-08 WO disclosed
EP-1899332-A1 PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING HEPATITIS C. GILEAD SCIENCES, INC. (US) 2008-03-19 EP disclosed
US-20080004285-A1 PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT 4 AZA IP NV (BE) 2008-01-03 US disclosed
US-20070232627-A1 ANTI-VIRAL COMPOUNDS ABBVIE INC. 2007-10-04 US disclosed
EP-1831217-A2 PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT 4 AZA IP NV (BE) 2007-09-12 EP disclosed
WO-2006135993-A1 PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING HEPATITIS C. GILEAD SCIENCES, INC. (US) 2006-12-28 WO disclosed
WO-2006069805-A2 PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT 4 AZA IP NV (BE) 2006-07-06 WO disclosed
US-5908960-A Compounds SMITHKLINE BEECHAM CORPORATION (US) 1999-06-01 US disclosed
US-5252450-A Organic capping group attached to multivalent metal ions integrated into the surface BATTELLE MEMORIAL INSTITUTE (US) 1993-10-12 US disclosed
WO-1992013927-A1 CAPPED PHOTOCHROMIC SILVER COMPOSITIONS FOR INCORPORATION INTO A PLASTIC MATRIX BATTELLE MEMORIAL INSTITUTE (US) 1992-08-20 WO disclosed