Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP7 | P09237 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14564029 | 1.00 | HTT (0.61) | HTTSMN1; SMN2NPC1RAB9AGRIN2B | |
| SCHEMBL14347695 | 1.00 | HTT (0.61) | HTTSMN1; SMN2NPC1RAB9AGRIN2B | |
| SCHEMBL2527774 | 0.93 | HTT (0.67) | HTTSMN1; SMN2NPC1RAB9AGRIN2B | |
| SCHEMBL23187612 | 0.90 | HTT (0.57) | HTTSMN1; SMN2NPC1RAB9AGRIN2B | |
| SCHEMBL4671370 | 0.87 | SMN1; SMN2 (0.63) | HTTSMN1; SMN2NPC1RAB9AGRIN2B | |
| SCHEMBL28563410 | 0.86 | SMN1; SMN2 (0.61) | HTTSMN1; SMN2NPC1RAB9AGRIN2B | |
| SCHEMBL21939748 | 0.86 | SMN1; SMN2 (0.61) | HTTSMN1; SMN2NPC1RAB9AGRIN2B | |
| SCHEMBL14235053 | 0.86 | HTT (0.54) | HTTSMN1; SMN2NPC1RAB9AGRIN2B | |
| SCHEMBL14235517 | 0.86 | HTT (0.54) | HTTSMN1; SMN2NPC1RAB9AGRIN2B | |
| SCHEMBL14127628 | 0.86 | HTT (0.54) | HTTSMN1; SMN2NPC1RAB9AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066584-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066584-A1 | Amido compounds and their use as pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | HTT 3487/4885SMN1; SMN2 3627/4885NPC1 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.