Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.65 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.64 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | OSBP | P22059 | 1/20 | 0.59 |
| ▸ | RORC | P51449 | 1/20 | 0.59 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.59 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.53 |
| ▸ | FGF2 | P09038 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 2/20 | 0.52 |
| ▸ | UGCG | Q16739 | 2/20 | 0.52 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23876215 | 0.95 | POLA1 (0.68) | POLA1CYP46A1PLA2G2AUSP2LMNA | |
| SCHEMBL12325985 | 0.94 | CYP46A1 (0.68) | POLA1CYP46A1PLA2G2AUSP2LMNA | |
| SCHEMBL30862604 | 0.91 | POLA1 (0.72) | POLA1CYP46A1PLA2G2AUSP2LMNA | |
| SCHEMBL22292573 | 0.91 | POLA1 (0.72) | POLA1CYP46A1PLA2G2AUSP2LMNA | |
| SCHEMBL33528291 | 0.91 | POLA1 (0.72) | POLA1CYP46A1PLA2G2AUSP2LMNA | |
| SCHEMBL26910780 | 0.91 | POLA1 (0.77) | POLA1CYP46A1PLA2G2AUSP2LMNA | |
| SCHEMBL330612 | 0.91 | POLA1 (0.77) | POLA1CYP46A1PLA2G2AUSP2LMNA | |
| SCHEMBL25992010 | 0.91 | POLA1 (0.62) | POLA1CYP46A1PLA2G2AUSP2LMNA | |
| SCHEMBL20620339 | 0.91 | POLA1 (0.62) | POLA1CYP46A1PLA2G2AUSP2LMNA | |
| SCHEMBL15371975 | 0.91 | POLA1 (0.70) | POLA1CYP46A1PLA2G2AUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764089-A1 | Serum stable liposomes comprising amphoter II lipid mixtures | Novosom AG (DE) | 2007-03-21 | — | — | EP | disclosed |