Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17193155 | 0.85 | HTR4 (1.00) | HTR4 | |
| Hydrochloric Acid SCHEMBL2942576 | 0.84 | HTR4 (0.98) | HTR4 | |
| SCHEMBL7954351 | 0.83 | HTR4 (1.00) | HTR4 | |
| SCHEMBL13479954 | 0.79 | HTR4 (0.80) | HTR4 | |
| SCHEMBL13036124 | 0.78 | HTR4 (0.78) | HTR4 | |
| SCHEMBL7944045 | 0.78 | HTR4 (1.00) | HTR4 | |
| SCHEMBL7943943 | 0.77 | HTR4 (1.00) | HTR4 | |
| SCHEMBL7952854 | 0.75 | HTR4 (1.00) | HTR4 | |
| SCHEMBL13036125 | 0.75 | HTR4 (0.73) | HTR4 | |
| SCHEMBL7952197 | 0.75 | HTR4 (1.00) | HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112270-B1 | DIHYDROBENZODIOXINE CARBOXAMIDE AND KETONE DERIVATIVES AS 5-HT4 RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2007-03-21 | — | — | EP | disclosed |