Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.65 |
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13675679 | 0.94 | TRPV1 (0.72) | TRPV1NPC1RAB9AMAOBMEN1 | |
| SCHEMBL4002352 | 0.82 | TRPV1 (0.76) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13675680 | 0.79 | TRPV1 (1.00) | TRPV1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5171565 | 0.78 | RAB9A (1.00) | NPC1RAB9AMAOBMEN1KMT2A | |
| SCHEMBL13675707 | 0.76 | TRPV1 (0.91) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3998005 | 0.76 | TRPV1 (1.00) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3998011 | 0.76 | TRPV1 (1.00) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13675900 | 0.75 | TRPV1 (1.00) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13675708 | 0.75 | TRPV1 (0.89) | TRPV1NPC1RAB9AMAOBMEN1 | |
| SCHEMBL13675709 | 0.75 | TRPV1 (0.89) | TRPV1RAB9AMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764358-A2 | Cyclic amides as vanilloid receptor ligands and their use in treatments of inflammatory and neuropathic pain | Amgen, Inc (US) | 2007-03-21 | — | — | EP | disclosed |