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Sugi Predict / Compounds / SCHEMBL14566711

SCHEMBL14566711

SCHEMBL14566711

CC(=O)NC[C@H]1CN(c2ccc(-c3ccc(N4CCN(C(=O)OCC5=CC=CCC5)CC4)c(F)c3)c(F)c2)C(=O)O1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 6/20 0.56
▸ MAOB P27338 6/20 0.56
▸ PTGS1 P23219 2/20 0.56
▸ SDHA P31040 2/20 0.56
▸ LMNA P02545 1/20 0.56
▸ CALML3 P27482 1/20 0.56
▸ TOP2B Q02880 1/20 0.47
▸ F10 P00742 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4173980 0.86 MAOA (0.60) MAOAMAOBPTGS1SDHALMNA
SCHEMBL13945012 0.86 MAOA (0.60) MAOAMAOBPTGS1SDHALMNA
SCHEMBL4163039 0.82 MAOA (0.67) MAOAMAOBPTGS1SDHALMNA
SCHEMBL4181831 0.81 MAOA (0.71) MAOAMAOBPTGS1SDHALMNA
SCHEMBL4181827 0.81 MAOA (0.71) MAOAMAOBPTGS1SDHALMNA
SCHEMBL4168125 0.81 MAOA (0.74) MAOAMAOBPTGS1SDHALMNA
SCHEMBL14612500 0.81 MAOB (0.74) MAOAMAOBPTGS1SDHALMNA
SCHEMBL4168120 0.81 MAOA (0.74) MAOAMAOBPTGS1SDHALMNA
SCHEMBL5323788 0.80 MAOB (0.67) MAOAMAOBPTGS1SDHALMNA
SCHEMBL1498671 0.80 MAOB (0.67) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007023507-A2 OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION WOCKHARDT LIMITED (IN) 2007-03-01 — — WO disclosed
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