Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.52 |
| ▸ | GPR183 | P32249 | 1/20 | 0.51 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13359565 | 0.86 | LSS (0.59) | HPGDSIGMAR1HRH3GPR183MBTD1 | |
| SCHEMBL522513 | 0.83 | HPGD (0.75) | HPGDSIGMAR1HRH3GPR183 | |
| SCHEMBL1579365 | 0.81 | HRH3 (0.52) | HPGDHRH3GPR183MBTD1L3MBTL3 | |
| SCHEMBL1449644 | 0.80 | HRH3 (0.75) | ALDH1A1HRH3GPR183MBTD1L3MBTL3 | |
| SCHEMBL1177159 | 0.80 | HRH3 (0.79) | HRH3GPR183 | |
| SCHEMBL27789125 | 0.79 | KDM4E (0.61) | ALDH1A1L3MBTL1 | |
| SCHEMBL8358137 | 0.78 | SIGMAR1 (0.81) | HPGDALDH1A1SIGMAR1L3MBTL3L3MBTL1 | |
| SCHEMBL1449894 | 0.78 | HRH3 (0.76) | ALDH1A1HRH3MBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL8934917 | 0.77 | SIGMAR1 (0.64) | HPGDALDH1A1SIGMAR1L3MBTL3L3MBTL1 | |
| SCHEMBL15763177 | 0.77 | KDM4E (0.59) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007035425-A2 | CYCLOPROPYL AMINES AS MODULATORS OF THE HISTAMINE H3 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-03-29 | — | — | WO | disclosed |