Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1137096 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP11B1CYP11B2GAAMEN1 | |
| SCHEMBL7809671 | 0.68 | MEN1 (0.63) | SMN1; SMN2GAAMEN1MAPTCYP2C9 | |
| SCHEMBL9846980 | 0.67 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP11B1CYP11B2GAAMEN1 | |
| SCHEMBL8017634 | 0.67 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP11B1CYP11B2GAAMEN1 | |
| SCHEMBL3064009 | 0.67 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP11B1CYP11B2GAAMEN1 | |
| SCHEMBL30034215 | 0.67 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP11B1CYP11B2GAAMEN1 | |
| SCHEMBL5135302 | 0.66 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP11B1CYP11B2GAAMAPT | |
| SCHEMBL29405346 | 0.65 | MAPT (0.50) | SMN1; SMN2MEN1MAPTCYP2C9KMT2A | |
| SCHEMBL984999 | 0.65 | MAPT (0.50) | SMN1; SMN2MEN1MAPTCYP2C9KMT2A | |
| Diphenylmethanol SCHEMBL11564700 | 0.65 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007033196-A1 | MET KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-03-22 | — | — | WO | disclosed |