Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 15/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.52 |
| ▸ | HTR2A | P28223 | 10/20 | 0.46 |
| ▸ | HTR2B | P41595 | 10/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13751958 | 1.00 | HTR2C (0.67) | HTR2CSLC6A4HTR2AHTR2BCNR1 | |
| SCHEMBL14568453 | 1.00 | HTR2C (0.67) | HTR2CSLC6A4HTR2AHTR2BCNR1 | |
| SCHEMBL13751899 | 0.89 | HTR2C (0.70) | HTR2CSLC6A4HTR2AHTR2BCNR1 | |
| SCHEMBL13751942 | 0.89 | HTR2C (0.70) | HTR2CSLC6A4HTR2AHTR2BCNR1 | |
| SCHEMBL14568825 | 0.86 | HTR2C (0.67) | HTR2CSLC6A4HTR2AHTR2BSLC6A3 | |
| SCHEMBL14568550 | 0.85 | HTR2C (0.62) | HTR2CSLC6A4HTR2AHTR2BCNR1 | |
| SCHEMBL14568836 | 0.83 | SLC6A4 (0.56) | HTR2CSLC6A4HTR2BSLC6A3KDM1A | |
| SCHEMBL14568552 | 0.83 | HTR2C (0.52) | HTR2CSLC6A4HTR2AHTR2BKDM1A | |
| SCHEMBL13742184 | 0.81 | HTR2C (0.97) | HTR2CSLC6A4HTR2AHTR2BSLC6A3 | |
| SCHEMBL13742720 | 0.81 | HTR2C (0.97) | HTR2CSLC6A4HTR2AHTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025144-A1 | 5-HT2C RECEPTOR AGONISTS AS ANORECTIC AGENTS | UNIVERSITY OF ILLINOIS - CHICAGO (US) | 2007-03-01 | — | — | WO | disclosed |