Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 6/20 | 0.45 |
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13751935 | 0.88 | HTR2C (0.50) | HTR2CHTR2AHTR2BKDM1AMAOA | |
| SCHEMBL14568822 | 0.86 | HTR2C (0.57) | HTR2CSLC6A4HTR2AHTR2BKDM1A | |
| SCHEMBL14568825 | 0.85 | HTR2C (0.67) | HTR2CSLC6A4HTR2AHTR2BSLC6A2 | |
| SCHEMBL14568262 | 0.83 | HTR2C (0.67) | HTR2CSLC6A4HTR2AHTR2BKDM1A | |
| SCHEMBL13751958 | 0.83 | HTR2C (0.67) | HTR2CSLC6A4HTR2AHTR2BKDM1A | |
| SCHEMBL14568453 | 0.83 | HTR2C (0.67) | HTR2CSLC6A4HTR2AHTR2BKDM1A | |
| SCHEMBL13742311 | 0.83 | HTR2C (0.71) | HTR2CSLC6A4HTR2AHTR2BKDM1A | |
| Hydrochloric Acid SCHEMBL4126137 | 0.82 | HTR2C (0.73) | HTR2CSLC6A4HTR2AHTR2BKDM1A | |
| Hydrochloric Acid SCHEMBL4126134 | 0.82 | HTR2C (0.73) | HTR2CSLC6A4HTR2AHTR2BKDM1A | |
| SCHEMBL4138978 | 0.80 | HTR2C (0.43) | HTR2CHTR2AHTR2BKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025144-A1 | 5-HT2C RECEPTOR AGONISTS AS ANORECTIC AGENTS | UNIVERSITY OF ILLINOIS - CHICAGO (US) | 2007-03-01 | — | — | WO | disclosed |