Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 18/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9913782 | 0.91 | SCNN1A (0.68) | SCNN1A | |
| SCHEMBL10062414 | 0.81 | SCNN1A (0.60) | SCNN1A | |
| SCHEMBL12251653 | 0.81 | SCNN1A (0.55) | SCNN1A | |
| SCHEMBL12251668 | 0.81 | SCNN1A (0.55) | SCNN1A | |
| SCHEMBL13907673 | 0.81 | SCNN1A (0.54) | SCNN1A | |
| SCHEMBL10062650 | 0.81 | SCNN1A (0.67) | SCNN1A | |
| SCHEMBL2331940 | 0.80 | SCNN1A (0.58) | SCNN1A | |
| SCHEMBL13912813 | 0.80 | SCNN1A (0.54) | SCNN1A | |
| SCHEMBL2054438 | 0.79 | SCNN1A (0.54) | SCNN1A | |
| SCHEMBL16808735 | 0.79 | SCNN1A (0.54) | SCNN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192960-B2 | Antihistamines; bronchodilators; antiinflammatory agents; inflammatory bowel disorders | PARION SCIENCES, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-7186833-B2 | Such as 4-(4-hydroxyphenyl)butylamidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride; time-release agents; for therapy of chronic bronchitis, emphysema, cystic fibrosis, and eye disorders | PARION SCIENCES, INC. (US) | 2007-03-06 | — | — | US | disclosed |