Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 2/20 | 0.33 |
| ▸ | CTRC | Q99895 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL650921 | 0.94 | MEP1B (0.38) | TSHRBACE1PPARDPPARAPPARG | |
| SCHEMBL14607026 | 0.94 | TSHR (0.40) | TSHRBACE1PPARDPPARALMNA | |
| SCHEMBL650063 | 0.92 | BCHE (0.38) | TSHRBACE1PPARDPPARAPPARG | |
| SCHEMBL5137098 | 0.89 | TSHR (0.44) | TSHRC5AR1TP53HSD11B1CMA1 | |
| SCHEMBL651086 | 0.86 | C5AR1 (0.52) | TSHRPPARAPPARGLMNAC5AR1 | |
| SCHEMBL5137996 | 0.85 | TSHR (0.41) | TSHRPPARAPPARGC5AR1ALDH1A1 | |
| SCHEMBL5138093 | 0.82 | TSHR (0.43) | TSHRLMNAALDH1A1HTTTP53 | |
| SCHEMBL14415595 | 0.82 | HPGD (0.44) | TSHRPPARAPPARGALDH1A1BCHE | |
| SCHEMBL5136036 | 0.82 | TSHR (0.45) | TSHRLMNAC5AR1ALDH1A1HTT | |
| SCHEMBL5137319 | 0.82 | TSHR (0.47) | TSHRC5AR1BCHETP53HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186734-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NEUROGEN CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |