SCHEMBL1457293

SCHEMBL1457293

CCCCCCCCCCCCCCCC(=O)OC1CC1

nearest known ligand 0.86

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.86
DGKA P23743 1/20 0.53
LMNA P02545 2/20 0.50
PRKCA P17252 5/20 0.49
PAM P19021 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16046795 1.00 NAAA (0.86) NAAADGKALMNAPRKCAPAM
SCHEMBL1457470 1.00 NAAA (0.86) NAAADGKALMNAPRKCAPAM
SCHEMBL30915389 1.00 NAAA (0.86) NAAADGKALMNAPRKCAPAM
SCHEMBL28110502 1.00 NAAA (0.86) NAAADGKALMNAPRKCAPAM
SCHEMBL27913647 1.00 NAAA (0.86) NAAADGKALMNAPRKCAPAM
SCHEMBL4978268 0.98 NAAA (0.82) NAAADGKALMNAPRKCAPAM
SCHEMBL3654640 0.92 NAAA (1.00) NAAADGKALMNAPRKCASMN1; SMN2
SCHEMBL9800900 0.92 NAAA (1.00) NAAADGKALMNAPRKCASMN1; SMN2
SCHEMBL3660392 0.92 NAAA (1.00) NAAADGKALMNAPRKCASMN1; SMN2
SCHEMBL1456468 0.92 NAAA (1.00) NAAADGKALMNAPRKCASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592418-B1 USE OF ENDOCANNABINOID-LIKE COMPOUNDS FOR TREATING CNS DEGENERATIVE DISORDERS RES & INNOVATION S P A (IT) 2017-09-06 EP disclosed
EP-1900365-B9 Endocannabinoid-like compounds and their use for treating dermatitis RES & INNOVATION S P A (IT) 2012-01-18 EP disclosed
EP-1900365-B1 Endocannabinoid-like compounds and their use for treating dermatitis RES & INNOVATION S P A (IT) 2011-03-30 EP disclosed
EP-1900365-A2 New endocannabinoid-like compounds and their use RESEARCH & INNOVATION SOC. COOP. A R.L. (IT) 2008-03-19 EP disclosed
EP-1592418-A2 USE IN THERAPY OF ENDOCANNABINOID-LIKE COMPOUNDS Research & Innovation Soc. Coop. A R.L. (IT) 2005-11-09 EP disclosed
WO-2004069240-A2 USE IN THERAPY OF ENDOCANNABINOID-LIKE COMPOUNDS RESEARCH & INNOVATION SOC. COOP. A. R. L. (IT) 2004-08-19 WO disclosed