Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764669 | 0.90 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL5777425 | 0.87 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL14573152 | 0.87 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL5746077 | 0.87 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL5750711 | 0.86 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL5751255 | 0.86 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL14573154 | 0.86 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL14573146 | 0.86 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL14341382 | 0.86 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL5750809 | 0.85 | KCNH2 (0.38) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186730-B2 | Bicyclic nitrogen-containing heterocyclic derivatives for use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2007-03-06 | — | — | US | disclosed |
| US-7186730-B2 | Bicyclic nitrogen-containing heterocyclic derivatives for use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2007-03-06 | — | — | US | disclosed |