Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 11/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5765881 | 0.91 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL6664492 | 0.86 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL14573145 | 0.86 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL14573144 | 0.83 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL14573143 | 0.83 | KCNH2 (0.55) | KCNH2 | |
| SCHEMBL14573147 | 0.83 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL14573146 | 0.82 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL14573142 | 0.81 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL5763984 | 0.77 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL14573148 | 0.77 | KCNH2 (0.47) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186730-B2 | Bicyclic nitrogen-containing heterocyclic derivatives for use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2007-03-06 | — | — | US | disclosed |
| US-7186730-B2 | Bicyclic nitrogen-containing heterocyclic derivatives for use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2007-03-06 | — | — | US | disclosed |