Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389688 | 0.87 | PARP1 (0.76) | PARP1 | |
| SCHEMBL12798158 | 0.86 | PARP1 (0.75) | PARP1 | |
| SCHEMBL863338 | 0.84 | PARP1 (0.92) | PARP1 | |
| SCHEMBL29408705 | 0.84 | PARP1 (0.92) | PARP1 | |
| SCHEMBL4437930 | 0.84 | PARP1 (1.00) | PARP1 | |
| SCHEMBL3389570 | 0.83 | PARP1 (0.71) | PARP1 | |
| SCHEMBL3388610 | 0.83 | PARP1 (1.00) | PARP1 | |
| SCHEMBL24390012 | 0.83 | PARP1 (0.70) | PARP1 | |
| SCHEMBL29565339 | 0.83 | PARP1 (0.70) | PARP1 | |
| SCHEMBL3385144 | 0.83 | PARP1 (0.80) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196085-B2 | Phthalazinone derivatives | KUDOS PHARMACEUTICALS LIMITED (GB) | 2007-03-27 | — | — | US | disclosed |
| US-7196085-B2 | Phthalazinone derivatives | KUDOS PHARMACEUTICALS LIMITED (GB) | 2007-03-27 | — | — | US | disclosed |