Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12107118 | 0.92 | TNKS2 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2TNKS2 | |
| SCHEMBL7268054 | 0.91 | NPC1 (0.39) | NPC1RAB9AALDH1A1SMN1; SMN2TNKS2 | |
| SCHEMBL14213069 | 0.89 | NPC1 (0.34) | NPC1RAB9AALDH1A1SMN1; SMN2TNKS2 | |
| SCHEMBL93349 | 0.87 | POLB (0.38) | NPC1RAB9AALDH1A1SMN1; SMN2TNKS2 | |
| SCHEMBL29404702 | 0.87 | POLB (0.38) | NPC1RAB9AALDH1A1SMN1; SMN2TNKS2 | |
| SCHEMBL4445599 | 0.85 | NPC1 (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL15867571 | 0.83 | NPC1 (0.39) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14577960 | 0.83 | NPC1 (0.34) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1004781 | 0.81 | TNKS2 (0.43) | TNKS2POLB | |
| SCHEMBL7268063 | 0.81 | NPC1 (0.46) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173071-B2 | Photo-cured and stabilized coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |