Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14577828 | 0.90 | NPC1 (0.31) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL14577978 | 0.83 | NPC1 (0.31) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL14577752 | 0.83 | NPC1 (0.36) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL5357262 | 0.81 | GAA (0.35) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL7532425 | 0.80 | — | — | |
| SCHEMBL8040272 | 0.78 | MAOB (0.32) | — | |
| SCHEMBL8039851 | 0.78 | MAOB (0.32) | — | |
| SCHEMBL7525894 | 0.77 | ADRB2 (0.31) | — | |
| SCHEMBL4445599 | 0.76 | NPC1 (0.40) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL6862565 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173071-B2 | Photo-cured and stabilized coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |