Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825259 | 1.00 | GSK3B (0.58) | GSK3BMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL12750110 | 0.89 | LMNA (0.48) | GSK3BMAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL13514454 | 0.80 | LMNA (0.42) | GSK3BMAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL12603677 | 0.80 | CYP1A2 (0.51) | MAPTALDH1A1KMT2AL3MBTL1RAB9A | |
| SCHEMBL12757030 | 0.80 | CA12 (0.45) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL8220014 | 0.80 | LMNA (0.42) | GSK3BMAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL16440164 | 0.80 | CYP1A2 (0.51) | MAPTALDH1A1KMT2AL3MBTL1RAB9A | |
| SCHEMBL6815200 | 0.80 | CYP1A2 (0.51) | MAPTALDH1A1KMT2AL3MBTL1RAB9A | |
| SCHEMBL16322214 | 0.80 | CA12 (0.45) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7855930 | 0.78 | LMNA (0.41) | GSK3BMAPTL3MBTL1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |