Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979544 | 0.87 | HTT (0.43) | RAB9AKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL5341760 | 0.87 | HTT (0.43) | RAB9AKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL14578059 | 0.85 | KDM4E (0.42) | NPC1RAB9AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL557468 | 0.85 | MAPT (0.45) | NPC1RAB9AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL14564442 | 0.84 | MAPT (0.44) | NPC1RAB9AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL5165138 | 0.83 | CHRNA7 (0.47) | NPC1RAB9AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL14564410 | 0.82 | MAPT (0.44) | NPC1RAB9AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL14564506 | 0.81 | MAPT (0.43) | NPC1RAB9AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL344007 | 0.81 | MAPT (0.43) | NPC1RAB9AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL14612049 | 0.81 | KMT2A (0.46) | RAB9AKDM4EHTTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |