Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341760 | 1.00 | HTT (0.43) | HTTSMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL14578059 | 0.91 | KDM4E (0.42) | HTTSMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL9979577 | 0.90 | HTT (0.41) | HTTSMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL9979612 | 0.90 | HTT (0.41) | HTTSMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL14612049 | 0.90 | KMT2A (0.46) | HTTSMN1; SMN2KDM4EGAAMAPT | |
| SCHEMBL14578299 | 0.89 | HTT (0.45) | HTTSMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL14578213 | 0.88 | HTT (0.40) | HTTSMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL14578227 | 0.88 | SMN1; SMN2 (0.41) | HTTSMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL14578300 | 0.88 | ABCG2 (0.36) | HTTSMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL13215927 | 0.88 | HTT (0.40) | HTTSMN1; SMN2KDM4ETDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |