Quingestrone

Quingestrone

SCHEMBL145789

CC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C=C(OC5CCCC5)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 0.58
SRD5A1 P18405 4/20 0.58
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
LMNA P02545 5/20 0.53
SHBG P04278 2/20 0.53
SERPINA6 P08185 2/20 0.53
G6PD P11413 1/20 0.53
CYP3A4 P08684 3/20 0.52
PMP22 Q01453 2/20 0.52
GRIN2D O15399 1/20 0.52
GRIN2A Q12879 1/20 0.52
GRIN2B Q13224 1/20 0.52
GRIN2C Q14957 1/20 0.52
CYP46A1 Q9Y6A2 1/20 0.52
HSD17B10 Q99714 1/20 0.52
THRB P10828 1/20 0.52
CYP2C9 P11712 2/20 0.50
TSHR P16473 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13265741 0.88 SRD5A2 (0.62) SRD5A2SRD5A1MEN1KMT2ATDP1
SCHEMBL7622300 0.88 SRD5A2 (0.62) SRD5A2SRD5A1MEN1KMT2ATDP1
SCHEMBL370474 0.88 SRD5A2 (0.62) SRD5A2SRD5A1MEN1KMT2ATDP1
SCHEMBL30332128 0.87 SRD5A2 (0.61) SRD5A2SRD5A1MEN1KMT2ATDP1
SCHEMBL14729818 0.87 SRD5A2 (0.61) SRD5A2SRD5A1MEN1KMT2ATDP1
SCHEMBL11213645 0.85 SRD5A2 (0.59) SRD5A2SRD5A1MEN1KMT2ATDP1
SCHEMBL13240146 0.83 SRD5A2 (0.58) SRD5A2SRD5A1MEN1KMT2ATDP1
SCHEMBL13378032 0.82 AR (0.71) SRD5A2SRD5A1MEN1KMT2ATDP1
SCHEMBL14726730 0.82 AR (0.71) SRD5A2SRD5A1MEN1KMT2ATDP1
SCHEMBL11515941 0.82 SRD5A2 (0.65) SRD5A2SRD5A1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 856 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3863708-B1 MIXED IONIC CONDUCTORS AND CORRESPONDING DEVICES, SYSTEMS AND METHODS OF MAKING BATTELLE MEMORIAL INSTITUTE (US) 2024-09-11 EP claimed
US-20160008376-A1 Compositions, Methods and Uses for Treating Gender-Biased Immune Disorders BIOCOPEA LIMITED (GB) 2016-01-14 US claimed
WO-2016005599-A1 COMPOSITIONS, METHODS AND USES FOR TREATING GENDER-BIASED IMMUNE DISORDERS BIOCOPEA LIMITED (GB) 2016-01-14 WO claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
CN-103284955-A Long-acting progestational hormone controlled-release injection implant and preparation method thereof SHANGHAI INST PLANNED PARENTHOOD RES 2013-09-11 CN claimed
US-20130131027-A1 PARENTERAL PHARMACEUTICAL FORM WHICH RELEASES AROMATSE INHIBITOR AND GESTAGENS, FOR THE TREATMENT OF ENDOMETRIOSIS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-05-23 US claimed
CN-103002873-A Parenteral pharmaceutical form which releases aromatse inhibitor and gestagens, for the treatment of endometriosis Bayer Pharma AG 2013-03-27 CN claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
US-20110195114-A1 TRANSDERMAL DELIVERY SYSTEMS FOR ACTIVE AGENTS ANTARES PHARMA, IPL, AG 2011-08-11 US claimed
WO-1991000095-A1 COMPOSITIONS USEFUL AS CONTRACEPTIVES IN MALES COHEN MICHAEL (NL) 1991-01-10 WO claimed
CN-1047974-A Compositions and methods for effecting contraception COHEN MICHAEL (NL) 1990-12-26 CN claimed
WO-1990014084-A1 USE OF MELATONIN DERIVATIVES FOR EFFECTING CONTRACEPTION COHEN MICHAEL (NL) 1990-11-29 WO claimed
EP-0354921-A1 COMPOSITIONS AND METHODS OF EFFECTING CONTRACEPTION AND CONTROL OF BREAST CANCER. APPLIED MED RES (US) 1990-02-21 EP claimed
US-4855305-A Compositions and methods of effecting contraception utilizing melatonin APPLIED MEDICAL RESEARCH (US) 1989-08-08 US claimed
WO-1988007370-A1 COMPOSITIONS AND METHODS OF EFFECTING CONTRACEPTION AND CONTROL OF BREAST CANCER APPLIED MEDICAL RESEARCH, LTD. (US) 1988-10-06 WO claimed
US-4346709-A Drug delivery devices comprising erodible polymer and erosion rate modifier ALZA CORPORATION (US) 1982-08-31 US claimed
US-4016270-A Method for treating dysmenorrhea with a uterine therapeutic system ALZA CORPORATION (US) 1977-04-05 US claimed
US-3942641-A Dispensing packages containing novel cyclic progestogen-interrupted estrogen oral contraceptive regimens SYNTEX CORPORATION (PM) 1976-03-09 US claimed
US-3932635-A Novel cyclic progestogen-interrupted estrogen oral contraceptive regimens SYNTEX CORPORATION (PM) 1976-01-13 US claimed