Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.71 |
| ▸ | ESR1 | P03372 | 1/20 | 0.71 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.71 |
| ▸ | SRD5A2 | P31213 | 7/20 | 0.65 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.59 |
| ▸ | SHBG | P04278 | 2/20 | 0.59 |
| ▸ | G6PD | P11413 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13378032 | 1.00 | AR (0.71) | ARESR1ESR2SRD5A2SRD5A1 | |
| SCHEMBL11515941 | 0.89 | SRD5A2 (0.65) | ARESR1ESR2SRD5A2SRD5A1 | |
| SCHEMBL13265741 | 0.86 | SRD5A2 (0.62) | ARESR1ESR2SRD5A2SRD5A1 | |
| SCHEMBL370474 | 0.86 | SRD5A2 (0.62) | ARESR1ESR2SRD5A2SRD5A1 | |
| SCHEMBL7622300 | 0.86 | SRD5A2 (0.62) | ARESR1ESR2SRD5A2SRD5A1 | |
| SCHEMBL30332128 | 0.85 | SRD5A2 (0.61) | ARESR1ESR2SRD5A2SRD5A1 | |
| SCHEMBL14729818 | 0.85 | SRD5A2 (0.61) | ARESR1ESR2SRD5A2SRD5A1 | |
| SCHEMBL5166591 | 0.83 | ESR1 (1.00) | ARESR1ESR2LMNASERPINA6 | |
| SCHEMBL5166597 | 0.83 | ESR1 (1.00) | ARESR1ESR2LMNASERPINA6 | |
| SCHEMBL14430121 | 0.83 | ESR1 (1.00) | ARESR1ESR2LMNASERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809567-B2 | Method for producing silylenol ethers | KYOTO UNIVERSITY (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20130053567-A1 | METHOD FOR PRODUCING SILYLENOL ETHERS | KYOTO UNIVERSITY (JP) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053567-A1 | METHOD FOR PRODUCING SILYLENOL ETHERS | AKR7A2, MSMO1, CYP2E1 | AR 527/4885ESR1 1633/4885ESR2 1342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.