Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 3/20 | 0.39 |
| ▸ | CCR8 | P51685 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14579756 | 0.93 | L3MBTL1 (0.47) | L3MBTL1NPC1HSP90AA1TLR7CCR1 | |
| SCHEMBL5486079 | 0.88 | TLR7 (0.51) | L3MBTL1NPC1HSP90AA1TLR7CCR1 | |
| SCHEMBL14579763 | 0.87 | CCR1 (0.43) | L3MBTL1NPC1HSP90AA1TLR7CCR1 | |
| SCHEMBL14579757 | 0.85 | CCR1 (0.46) | L3MBTL1NPC1HSP90AA1TLR7CCR1 | |
| SCHEMBL14579764 | 0.85 | NPC1 (0.40) | L3MBTL1NPC1HSP90AA1TLR7CCR1 | |
| SCHEMBL258866 | 0.83 | CCR1 (0.42) | L3MBTL1NPC1HSP90AA1TLR7CCR1 | |
| SCHEMBL14579760 | 0.81 | L3MBTL1 (0.47) | L3MBTL1NPC1HSP90AA1TLR7CCR1 | |
| SCHEMBL14579758 | 0.81 | CCR1 (0.47) | L3MBTL1NPC1HSP90AA1TLR7CCR1 | |
| SCHEMBL2297542 | 0.78 | NPC1 (0.44) | L3MBTL1NPC1HSP90AA1CCR1CCR8 | |
| SCHEMBL14579754 | 0.78 | CCR1 (0.40) | L3MBTL1NPC1HSP90AA1TLR7CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179542-B2 | Thiazole- and imidazole-fused phenanthroline molecules in organic light-emitting devices | CANON KABUSHIKI KAISHA (JP) | 2007-02-20 | — | — | US | disclosed |