Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | PDE1A | P54750 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14580668 | 0.87 | PDK2 (0.42) | PDK2NPY5RHSD11B1NR1I2PGR | |
| SCHEMBL14580656 | 0.85 | PDK2 (0.43) | PDK2PGR | |
| SCHEMBL15977673 | 0.84 | PDK2 (0.43) | PDK2NPY5RHSD11B1NR1I2PDE5A | |
| SCHEMBL15977814 | 0.84 | PDK2 (0.43) | PDK2NPY5RHSD11B1NR1I2PDE5A | |
| SCHEMBL14580658 | 0.84 | PDK2 (0.56) | PDK2NPY5RHSD11B1NR1I2CNR2 | |
| SCHEMBL15977594 | 0.83 | PDK2 (0.42) | PDK2NPY5RHSD11B1NR1I2PDE5A | |
| SCHEMBL12133807 | 0.83 | KDM4E (0.50) | PDK2NPY5RHSD11B1NR1I2PDE5A | |
| SCHEMBL19055690 | 0.82 | PDK2 (0.42) | PDK2NPY5RPGR | |
| SCHEMBL14580667 | 0.82 | KMT2A (0.42) | PDK2NPY5RKDM4ECYP1A2POLB | |
| SCHEMBL15977933 | 0.82 | PDK2 (0.43) | PDK2NPY5RHSD11B1NR1I2PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070042220-A1 | Compound having spiro bond, material for luminescent coating formation and organic electroluminescence element including the same | IDEMITSU KOSAN CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| US-20070042220-A1 | Compound having spiro bond, material for luminescent coating formation and organic electroluminescence element including the same | IDEMITSU KOSAN CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |