SCHEMBL14580656

SCHEMBL14580656

c1cc(-c2ccc3c(c2)C2(CCCC2)c2ccccc2-3)nc(-c2ccc3c(c2)C2(CCCC2)c2ccccc2-3)c1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 16/20 0.43
RARA P10276 1/20 0.38
RARB P10826 1/20 0.38
PGR P06401 2/20 0.37
MEN1 O00255 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14580659 0.89 PDK2 (0.40) PDK2PGR
SCHEMBL14612551 0.86 HPGD (0.37) PDK2PGRMEN1KMT2A
SCHEMBL14580676 0.86 PGR (0.38) PDK2PGRMEN1KMT2A
SCHEMBL10300919 0.85 PDK2 (0.37) PDK2RARARARBPGRMEN1
SCHEMBL10300938 0.85 MEN1 (0.36) PDK2RARARARBPGRMEN1
SCHEMBL14580657 0.85 PDK2 (0.57) PDK2PGR
SCHEMBL10300918 0.84 PGR (0.36) PDK2RARARARBPGRMEN1
SCHEMBL14580667 0.84 KMT2A (0.42) PDK2PGRMEN1RAB9AKMT2A
SCHEMBL14580660 0.83 PDK2 (0.42) PDK2MEN1RAB9AKMT2A
SCHEMBL15977933 0.82 PDK2 (0.43) PDK2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070042220-A1 Compound having spiro bond, material for luminescent coating formation and organic electroluminescence element including the same IDEMITSU KOSAN CO., LTD. (JP) 2007-02-22 US disclosed
US-20070042220-A1 Compound having spiro bond, material for luminescent coating formation and organic electroluminescence element including the same IDEMITSU KOSAN CO., LTD. (JP) 2007-02-22 US disclosed