Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 14/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14580671 | 0.94 | ESR1 (0.37) | ESR1ESR2PDK2MEN1MAPT | |
| SCHEMBL15274114 | 0.93 | MAOB (0.35) | ESR1ESR2PDK2MEN1MAPT | |
| SCHEMBL15274140 | 0.93 | MAOB (0.35) | ESR1ESR2PDK2MEN1MAPT | |
| SCHEMBL14580680 | 0.91 | ESR1 (0.36) | ESR1ESR2PDK2MEN1MAPT | |
| SCHEMBL14580660 | 0.86 | PDK2 (0.42) | ESR1ESR2PDK2MEN1KMT2A | |
| SCHEMBL14580669 | 0.86 | KMT2A (0.41) | ESR1ESR2PDK2MEN1MAPT | |
| SCHEMBL14580663 | 0.85 | PDK2 (0.39) | ESR1ESR2PDK2 | |
| SCHEMBL5505298 | 0.84 | ESR1 (0.40) | ESR1ESR2PDK2 | |
| SCHEMBL14580676 | 0.83 | PGR (0.38) | PDK2MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL14580658 | 0.81 | PDK2 (0.56) | ESR1ESR2PDK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070042220-A1 | Compound having spiro bond, material for luminescent coating formation and organic electroluminescence element including the same | IDEMITSU KOSAN CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| US-20070042220-A1 | Compound having spiro bond, material for luminescent coating formation and organic electroluminescence element including the same | IDEMITSU KOSAN CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |