Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 16/20 | 0.65 |
| ▸ | MEN1 | O00255 | 11/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.65 |
| ▸ | TP53 | P04637 | 8/20 | 0.65 |
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | XBP1 | P17861 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298458 | 0.87 | MAPT (0.48) | MAPTMEN1KMT2ATP53LMNA | |
| SCHEMBL12127306 | 0.80 | MAPT (0.69) | MAPTMEN1KMT2ATP53LMNA | |
| SCHEMBL16229980 | 0.78 | MAPT (0.66) | MAPTMEN1KMT2ATP53LMNA | |
| SCHEMBL12351248 | 0.78 | MAPT (1.00) | MAPTMEN1KMT2ATP53LMNA | |
| SCHEMBL6721369 | 0.78 | MAPT (0.82) | MAPTMEN1KMT2ATP53LMNA | |
| SCHEMBL6721418 | 0.78 | MAPT (0.79) | MAPTMEN1KMT2ATP53LMNA | |
| SCHEMBL6721359 | 0.78 | MAPT (0.81) | MAPTMEN1KMT2ATP53LMNA | |
| SCHEMBL6721389 | 0.77 | MAPT (1.00) | MAPTMEN1KMT2ATP53LMNA | |
| SCHEMBL15281361 | 0.72 | MAPT (1.00) | MAPTMEN1KMT2ATP53LMNA | |
| SCHEMBL6721415 | 0.72 | MAPT (1.00) | MAPTMEN1KMT2ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037785-A1 | Novel dipeptidyl peptidase IV inhibitors used for functionally influencing different cells and treating immunological, infammatory, neuronal, and other diseases | KEYNEUROTEK PHARMACEUTICALS AG (DE) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037785-A1 | Novel dipeptidyl peptidase IV inhibitors used for functionally influencing different cells and treating immunological, infammatory, neuronal, and other diseases | DNPEP, PREP, DPP4 | MAPT 1306/4885MEN1 3220/4885KMT2A 4135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.