Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14581052 | 0.87 | MAPT (0.65) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL2243385 | 0.72 | MMP2 (0.63) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL6589648 | 0.71 | MAPT (0.59) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL5145111 | 0.67 | MAPT (0.68) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL12127306 | 0.67 | MAPT (0.69) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL16229980 | 0.64 | MAPT (0.66) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL6595522 | 0.64 | KMT2A (0.66) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL6595519 | 0.64 | KMT2A (0.66) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL6721418 | 0.64 | MAPT (0.79) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL6721369 | 0.64 | MAPT (0.82) | MAPTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037779-A2 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS USED FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |