Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2923610 | 0.89 | ATM (0.64) | POLBALOX15TSHRMAPK1L3MBTL1 | |
| SCHEMBL3294932 | 0.87 | POLB (0.57) | POLBALOX15TSHRMAPK1L3MBTL1 | |
| SCHEMBL286034 | 0.86 | ALDH1A1 (0.61) | POLBALOX15TSHRMAPK1L3MBTL1 | |
| SCHEMBL286360 | 0.86 | GPBAR1 (0.62) | POLBALOX15TSHRMAPK1L3MBTL1 | |
| SCHEMBL2776267 | 0.86 | TSHR (0.70) | POLBALOX15TSHRMAPK1L3MBTL1 | |
| SCHEMBL13674 | 0.86 | CACNA1F (0.62) | POLBALOX15TSHRMAPK1L3MBTL1 | |
| SCHEMBL899450 | 0.86 | POLB (0.56) | POLBALOX15TSHRMAPK1L3MBTL1 | |
| SCHEMBL536297 | 0.86 | TSHR (0.74) | POLBALOX15TSHRMAPK1L3MBTL1 | |
| SCHEMBL2775071 | 0.85 | GAA (0.64) | POLBALOX15TSHRMAPK1L3MBTL1 | |
| SCHEMBL1776304 | 0.84 | MAPK1 (0.57) | POLBALOX15TSHRMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041694-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |