SCHEMBL14583153

SCHEMBL14583153

COCCOCCC(=O)NCC1OC(OP(=O)(O)OP(=O)(O)OCC2OC(n3ccc(=O)[nH]c3=O)[C@H](O)[C@@H]2O)[C@@H](O)[C@@H](O)[C@H]1O

nearest known ligand 0.68

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RY14 Q15391 11/20 0.68
P2RY2 P41231 6/20 0.68
P2RY6 Q15077 6/20 0.68
P2RY4 P51582 5/20 0.68
B4GALT1 P15291 4/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12361503 1.00 P2RY14 (0.68) P2RY14P2RY2P2RY6P2RY4B4GALT1
SCHEMBL14088636 1.00 P2RY14 (0.68) P2RY14P2RY2P2RY6P2RY4B4GALT1
SCHEMBL12015070 1.00 P2RY14 (0.68) P2RY14P2RY2P2RY6P2RY4B4GALT1
SCHEMBL14414538 1.00 P2RY14 (0.68) P2RY14P2RY2P2RY6P2RY4B4GALT1
SCHEMBL14095936 0.94 B4GALT1 (0.74) P2RY14P2RY2P2RY6P2RY4B4GALT1
SCHEMBL12108959 0.93 B4GALT1 (0.61) P2RY14P2RY2P2RY6P2RY4B4GALT1
SCHEMBL14027760 0.90 B4GALT1 (0.55) P2RY14P2RY2P2RY6P2RY4B4GALT1
SCHEMBL14178433 0.88 P2RY14 (0.75) P2RY14P2RY2P2RY6P2RY4
SCHEMBL1521165 0.88 P2RY14 (0.80) P2RY14P2RY2P2RY6P2RY4
SCHEMBL12132072 0.86 P2RY14 (0.78) P2RY14P2RY2P2RY6P2RY4B4GALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7179617-B2 Forming a convalent conjugate of a Factor IX peptide, removing X2 or a saccharyl subunit thereof from peptide forming a truncated glycan; contacting truncated glycan with glycosyltransferase and modified sugar donor under conditions suitable for glycosyltransferase to transfer a modified sugar moiety NEOSE TECHNOLOGIES, INC. (US) 2007-02-20 US disclosed