Lanosterol

Lanosterol

SCHEMBL145834

CC(C)=CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1CC3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 1.00
USP2 O75604 2/20 1.00
ALDH1A1 P00352 2/20 1.00
CYP3A4 P08684 2/20 1.00
ALOX15 P16050 2/20 1.00
CRYAB P02511 2/20 1.00
LMNA P02545 1/20 1.00
PTGES O14684 4/20 0.79
FNTA P49354 1/20 0.74
FNTB P49356 1/20 0.74
CRYAA P02489 1/20 0.71
ACHE P22303 1/20 0.62
MEN1 O00255 1/20 0.61
PLA2G1B P04054 1/20 0.61
DNMT1 P26358 1/20 0.61
BLM P54132 1/20 0.61
KMT2A Q03164 1/20 0.61
ATG4B Q9Y4P1 1/20 0.61
HMGCR P04035 1/20 0.61
PREP P48147 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lanosterol SCHEMBL16994483 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL14240642 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL14536063 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL14360758 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL2154745 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL145835 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL1696473 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL19194030 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL21348006 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL244737 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17473 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144751-A1 LIPOSOME COMPOSITIONS COMPRISING WEAK ACID DRUGS AND USES THEREOF PHARMOSA BIOPHARM INC. (TW) 2026-05-28 US claimed
US-20260144740-A1 COSMETIC ACTIVE INGREDIENT DERIVED FROM A NON-VOLATILE FRACTION OF CANARIUM EXUDATE AND USES THEREOF FLORE SCOLA (FR) 2026-05-28 US claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122080243-A Saccharide supermolecule emulsifier and preparation method and application thereof 2026-05-26 CN claimed
CN-122075388-A Ophthalmic compositions for treating vision disorders 2026-05-26 CN claimed
CN-122071427-A Amino lipid, preparation method and application thereof 中山大学孙逸仙纪念医院 2026-05-22 CN claimed
US-20260139254-A1 INTERFERING RNA FOR INHIBITING TOP1 GENE EXPRESSION AND USE THEREOF JENKEM TECH CO LTD BEIJING (CN) 2026-05-21 US claimed
CN-121270639-B Application of lanosterol derivative in preparing medicament for treating retinal degeneration disease 中山大学中山眼科中心 2026-05-19 CN claimed
CN-122056926-A Probiotic composition containing melatonin and application of composition in sleep 南京北极光生物科技有限公司 2026-05-19 CN claimed
CN-122060565-A Supercritical CO utilization2Method for preparing lanolin by extracting wool washing wastewater 烟台南山学院 2026-05-19 CN claimed
US-4260603-A Sterol glycoside with activity as prostaglandin synthetase inhibitor HOYER GMBH & CO. KG (DE) 1981-04-07 US claimed
US-4254111-A ANTIINFLAMMATORY STERYL GLYCOSIDE HEMIESTERS ROECAR HOLDINGS (NETHERLANDS ANTILLES) NV (NL) 1981-03-03 US claimed
WO-1980001242-A1 GALENICAL PREPARATION SANDOZ AG (CH) 1980-06-26 WO claimed
US-4196189-A Dental and oral hygiene preparations BLENDAX-WERKE R. SCHNEIDER (DE) 1980-04-01 US claimed
US-4192859-A MEDICAL DIAGNOSIS USING X-RAYS E. R. SQUIBB & SONS, INC. (US) 1980-03-11 US claimed
US-4188379-A Sterolins and their use ROECAR HOLDINGS (NETHERLANDS ANTILLES) N.V. (AN) 1980-02-12 US claimed
EP-0007474-A1 Sterolinhemiesters, process for their preparation and pharmaceutical compositions containing them Roecar Holdings (Netherlands Antilles) N.V. (AN) 1980-02-06 EP claimed
US-4169885-A DENTAL AND ORAL HYGIENE PREPARATIONS BLENDAX-WERKE R. SCHNEIDER GMBH & CO. (DE) 1979-10-02 US claimed
US-4124607-A Preparation of sterol substrates for bioconversion THE UPJOHN COMPANY (US) 1978-11-07 US claimed
US-3957971-A COSMETICS, LIPOSOMES, HUMECTANTS LEVER BROTHERS COMPANY (US) 1976-05-18 US claimed