Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 2/20 | 1.00 |
| ▸ | CRYAB | P02511 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | PTGES | O14684 | 4/20 | 0.79 |
| ▸ | FNTA | P49354 | 1/20 | 0.74 |
| ▸ | FNTB | P49356 | 1/20 | 0.74 |
| ▸ | CRYAA | P02489 | 1/20 | 0.71 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.61 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.61 |
| ▸ | HMGCR | P04035 | 1/20 | 0.61 |
| ▸ | PREP | P48147 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lanosterol SCHEMBL16994483 | 1.00 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL145834 | 1.00 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL14240642 | 1.00 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL14536063 | 1.00 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL14360758 | 1.00 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL2154745 | 1.00 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL145835 | 1.00 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL1696473 | 1.00 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL19194030 | 1.00 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL21348006 | 1.00 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11207333-B2 | Compositions comprising triterpenoids and uses thereof for treating optic neuropathy | REGENERA PHARMA LTD. (IL) | 2021-12-28 | — | — | US | claimed |
| US-11173164-B2 | Compositions comprising triterpenoids | REGENERA PHARMA LTD. (IL) | 2021-11-16 | — | — | US | claimed |
| EP-3352742-B1 | COMPOSITIONS COMPRISING TRITERPENOIDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND PARKINSON'S DISEASE | REGENERA PHARMA LTD (IL) | 2021-11-03 | — | — | EP | claimed |
| US-11083736-B2 | Compositions comprising triterpenoids | REGENERA PHARMA LTD. (IL) | 2021-08-10 | — | — | US | claimed |
| US-20200155569-A1 | COMPOSITIONS COMPRISING TRITERPENOIDS | REGENERA PHARMA LTD. (IL) | 2020-05-21 | — | — | US | claimed |
| US-10588911-B2 | Compositions comprising triterpenoids | REGENERA PHARMA LTD. (IL) | 2020-03-17 | — | — | US | claimed |
| US-20190314389-A1 | COMPOSITIONS COMPRISING TRITERPENOIDS | REGENERA PHARMA LTD. (IL) | 2019-10-17 | — | — | US | claimed |
| WO-2019170239-A1 | TERPENE ENRICHED FRACTIONS FREE FROM POLYTERPENES EXTRACTED FROM CHIOS MASTIC GUM AND COSMETIC, NUTRACEUTICAL, MEDICAL DEVICES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHYTOITALIA SRL (IT) | 2019-09-12 | — | — | WO | claimed |
| US-20190224217-A1 | COMPOSITIONS COMPRISING TRITERPENOIDS AND USES THEREOF FOR TREATING OPTIC NEUROPATHY | REGENERA PHARMA LTD. (IL) | 2019-07-25 | — | — | US | claimed |
| EP-3509699-A1 | COMPOSITIONS COMPRISING TRITERPENOIDS AND USES THEREOF FOR TREATING OPTIC NEUROPATHY | Regenera Pharma Ltd. (IL) | 2019-07-17 | — | — | EP | claimed |
| US-20110136773-A1 | Pharmaceutical Uses of Lanosta-8,24-dien-3-ols | AMAZONIA FITOMEDICAMENTOS LTDA (BR) | 2011-06-09 | — | — | US | claimed |
| EP-2323666-A1 | PHARMACEUTICAL USES OF LANOSTA-8,24-DIEN-3-OLS | Amazonia Fitomedicamentos Ltda (BR) | 2011-05-25 | — | — | EP | claimed |
| WO-2010015874-A1 | PHARMACEUTICAL USES OF LANOSTA-8,24-DIEN-3-OLS | AMAZONIA FITOMEDICAMENTOS LTDA (BR) | 2010-02-11 | — | — | WO | claimed |
| WO-2006007676-A1 | COMBINATION OF ACTIVE FRACTIONS FROM THE PLANTS EUPHORBIA TIRUCALLI L AND FICOS CARICA L. AND METHOD OF TREATING CANCER AND AIDS | AMAZÔNIA FITOMEDICAMENTOS LTDA. (BR) | 2006-01-26 | — | — | WO | claimed |
| US-20050238740-A1 | Use of mastic and its components for the control of microbial infections | THALLIUM HOLDING COMPANY, LLC | 2005-10-27 | — | — | US | claimed |
| EP-1501527-A1 | USE OF MASTIC AND ITS COMPONENTS FOR THE CONTROL OF MICROBIAL INFECTIONS | LAVIPHARM S.A. (GR) | 2005-02-02 | — | — | EP | claimed |
| WO-2003092712-A1 | USE OF MASTIC AND ITS COMPONENTS FOR THE CONTROL OF MICROBIAL INFECTIONS | LAVIPHARM S.A. (GR) | 2003-11-13 | — | — | WO | claimed |
| US-4748161-A | Triterpenyl esters of organic acids and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1988-05-31 | — | — | US | claimed |
| CN-85109752-A | Preparation triterpenoid organic acid ester and the method that contains the hypolipidemic agents of this compounds | — | 1986-12-17 | — | — | CN | claimed |
| EP-0166542-A2 | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1986-01-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11207333-B2 | Compositions comprising triterpenoids and uses thereof for treating optic neuropathy | AQP4, CYP27A1, PMP22 | MAPT 490/4885USP2 4207/4885ALDH1A1 1999/4885 |
| US-11173164-B2 | Compositions comprising triterpenoids | PARK7, SNCA, APP | MAPT 9/4885USP2 4026/4885ALDH1A1 3503/4885 |
| US-20200155569-A1 | COMPOSITIONS COMPRISING TRITERPENOIDS | PARK7, SNCA, APP | MAPT 9/4885USP2 4026/4885ALDH1A1 3503/4885 |
| US-20190224217-A1 | COMPOSITIONS COMPRISING TRITERPENOIDS AND USES THEREOF FOR TREATING OPTIC NEUROPATHY | AQP4, CYP27A1, PMP22 | MAPT 490/4885USP2 4207/4885ALDH1A1 1999/4885 |
| US-20190314389-A1 | COMPOSITIONS COMPRISING TRITERPENOIDS | CYP27A1, CYP11B2, CYP11B1 | MAPT 1829/4885USP2 4142/4885ALDH1A1 2491/4885 |
| US-11083736-B2 | Compositions comprising triterpenoids | CYP27A1, CYP11B2, CYP11B1 | MAPT 1829/4885USP2 4142/4885ALDH1A1 2491/4885 |
| US-10588911-B2 | Compositions comprising triterpenoids | PARK7, SNCA, APP | MAPT 9/4885USP2 4026/4885ALDH1A1 3503/4885 |
| US-20050238740-A1 | Use of mastic and its components for the control of microbial infections | CD14, RPL5, NFATC1 | MAPT 4056/4885USP2 3365/4885ALDH1A1 4837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.