Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 18/20 | 0.57 |
| ▸ | F2 | P00734 | 2/20 | 0.57 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14583974 | 0.91 | F2R (0.53) | F2RF2F2RL1 | |
| SCHEMBL14583985 | 0.80 | F2R (0.52) | F2RF2PSMB5 | |
| SCHEMBL30589701 | 0.79 | F2R (0.85) | F2RF2 | |
| SCHEMBL4263176 | 0.79 | F2R (0.85) | F2RF2 | |
| SCHEMBL12340165 | 0.78 | F2R (0.49) | F2RF2KLKB1 | |
| Hydrochloric Acid SCHEMBL29439912 | 0.78 | F2R (0.84) | F2RF2 | |
| Rwj-58259 SCHEMBL14090275 | 0.76 | F2R (0.83) | F2RF2F2RL1 | |
| SCHEMBL14090282 | 0.76 | F2R (0.74) | F2RF2F2RL1 | |
| SCHEMBL14583978 | 0.75 | F2R (0.77) | F2RF2 | |
| SCHEMBL13945250 | 0.74 | F2R (0.44) | F2RF2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183252-B2 | Indole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2007-02-27 | — | — | US | disclosed |