Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 14/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14583980 | 0.80 | F2R (0.57) | F2RF2PSMB5 | |
| SCHEMBL14583983 | 0.76 | F2R (0.82) | F2RF2 | |
| SCHEMBL14090286 | 0.70 | F2R (0.68) | F2RF2 | |
| SCHEMBL14583982 | 0.70 | GPR142 (0.45) | CTSLCTSS | |
| SCHEMBL14090294 | 0.69 | F2R (0.68) | F2RF2 | |
| SCHEMBL14090282 | 0.69 | F2R (0.74) | F2RF2 | |
| SCHEMBL5414423 | 0.67 | TACR2 (0.58) | — | |
| SCHEMBL5414433 | 0.67 | TACR2 (0.58) | — | |
| SCHEMBL12340165 | 0.67 | F2R (0.49) | F2RF2 | |
| SCHEMBL14090288 | 0.64 | GRIA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183252-B2 | Indole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2007-02-27 | — | — | US | disclosed |