Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 20/20 | 1.00 |
| ▸ | INSR | P06213 | 10/20 | 1.00 |
| ▸ | TEC | P42680 | 1/20 | 0.83 |
| ▸ | TXK | P42681 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14699309 | 0.81 | ITK (0.72) | ITKINSR | |
| SCHEMBL14698937 | 0.80 | ITK (0.84) | ITKINSR | |
| SCHEMBL14698857 | 0.80 | ITK (0.83) | ITKINSR | |
| SCHEMBL5576415 | 0.80 | ITK (0.69) | ITKINSR | |
| SCHEMBL6770253 | 0.79 | ITK (1.00) | ITK | |
| SCHEMBL5576414 | 0.79 | ITK (0.71) | ITKINSR | |
| SCHEMBL14698272 | 0.78 | ITK (0.70) | ITKINSR | |
| SCHEMBL14698895 | 0.78 | ITK (0.78) | ITKINSR | |
| SCHEMBL14708988 | 0.76 | ITK (0.64) | ITKINSRTECTXK | |
| SCHEMBL14699247 | 0.76 | ITK (0.84) | ITKINSRTXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032403-A1 | Crystal structure of the ITK kinase domain | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-02-08 | — | — | US | disclosed |
| US-20070032403-A1 | Crystal structure of the ITK kinase domain | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032403-A1 | Crystal structure of the ITK kinase domain | ITK, DTYMK, WEE1 | ITK 1/4885INSR 299/4885TEC 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.