Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | CRHBP | P24387 | 2/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15982300 | 1.00 | LMNA (0.52) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL15981871 | 1.00 | LMNA (0.52) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL14587292 | 1.00 | LMNA (0.52) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL15981877 | 1.00 | LMNA (0.52) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL456419 | 0.91 | ITGB2 (0.45) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL33274 | 0.91 | — | — | |
| SCHEMBL15982301 | 0.89 | LMNA (0.74) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL15981881 | 0.89 | LMNA (0.74) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL15981864 | 0.89 | LMNA (0.74) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL25248367 | 0.88 | ITGB2 (0.43) | LMNASMN1; SMN2CRHBPCRHR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183419-B2 | Reacting a 2,5-di(alkoxycarbonyl)-3,4-dihydroxythiophene or the alkali metal salt thereof with a ditosylate and cleaving the ester and decarboxylating the intermediate thus formed; used as monomers for pi-conjugated polymers | H.C. STARCK GMBH & CO. KG (DE) | 2007-02-27 | — | — | US | disclosed |
| US-7183419-B2 | Reacting a 2,5-di(alkoxycarbonyl)-3,4-dihydroxythiophene or the alkali metal salt thereof with a ditosylate and cleaving the ester and decarboxylating the intermediate thus formed; used as monomers for pi-conjugated polymers | H.C. STARCK GMBH & CO. KG (DE) | 2007-02-27 | — | — | US | disclosed |