Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GPX4 | P36969 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1437259 | 0.81 | CNR1 (0.41) | LMNARIPK1ALOX15 | |
| SCHEMBL2995161 | 0.78 | POLB (0.41) | LMNAALDH1A1RECQLALOX15NPC1 | |
| SCHEMBL1437208 | 0.78 | EGLN1 (0.35) | ALDH1A1MAOB | |
| SCHEMBL1437230 | 0.77 | CNR1 (0.40) | ALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL5806551 | 0.77 | ALDH1A1 (0.33) | ALDH1A1RECQLRAB9ASMN1; SMN2MAOB | |
| SCHEMBL31634153 | 0.76 | EGLN1 (0.49) | — | |
| SCHEMBL32662983 | 0.76 | KDM4E (0.45) | LMNASMN1; SMN2MAOBNAMPT | |
| SCHEMBL22372297 | 0.75 | HPGD (0.48) | LMNAALDH1A1RECQLNPC1RAB9A | |
| SCHEMBL10245943 | 0.75 | KDM4E (0.49) | LMNAALOX15NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1436858 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179907-B2 | Antibiotic compounds | SOMALOGIC OPERATING CO. INC. | 2007-02-20 | — | — | US | disclosed |
| US-7179907-B2 | Antibiotic compounds | SOMALOGIC OPERATING CO. INC. | 2007-02-20 | — | — | US | disclosed |