SCHEMBL14587482

SCHEMBL14587482

NC(=O)OCc1ccoc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.51
SLC1A3 P43003 1/20 0.51
SLC1A2 P43004 1/20 0.51
SLC1A1 P43005 1/20 0.51
CETP P11597 1/20 0.45
LMNA P02545 1/20 0.37
ACACB O00763 2/20 0.36
NQO1 P15559 1/20 0.36
PLK1 P53350 1/20 0.36
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
GABRA2 P47869 1/20 0.36
GABRB2 P47870 1/20 0.36
GABRA4 P48169 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4022806 0.81 ALDH1A1 (0.55) ALOX5SLC1A3SLC1A2SLC1A1CETP
SCHEMBL12321172 0.78 CETP (0.50) ALOX5SLC1A3SLC1A2SLC1A1CETP
SCHEMBL30437401 0.77 KMT2A (0.50) LMNANQO1CYP1A2CYP2D6PKM
SCHEMBL12193393 0.77 CETP (0.46) ALOX5SLC1A3SLC1A2SLC1A1CETP
SCHEMBL14587494 0.77 CETP (0.46) ALOX5SLC1A3SLC1A2SLC1A1CETP
SCHEMBL10033485 0.77 SLC1A3 (0.44) ALOX5SLC1A3SLC1A2SLC1A1CETP
SCHEMBL17717381 0.75 CETP (0.44) ALOX5SLC1A3SLC1A2SLC1A1CETP
SCHEMBL28689063 0.75 KMT2A (0.66) SLC1A3SLC1A2SLC1A1LMNASMN1; SMN2
SCHEMBL11659711 0.75 SLC1A3 (0.43) ALOX5SLC1A3SLC1A2SLC1A1CETP
SCHEMBL7744824 0.74 PARP1 (0.62) LMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7179907-B2 Antibiotic compounds SOMALOGIC OPERATING CO. INC. 2007-02-20 US disclosed
US-7179907-B2 Antibiotic compounds SOMALOGIC OPERATING CO. INC. 2007-02-20 US disclosed