Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.54 |
| ▸ | FNTB | P49356 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14588476 | 0.83 | FNTA (0.64) | FNTAFNTBKMT2ACYP3A4 | |
| SCHEMBL27251471 | 0.76 | FNTA (0.66) | FNTAFNTBCNR1CYP3A4 | |
| SCHEMBL14588486 | 0.75 | FNTA (0.46) | FNTAFNTBKMT2AMEN1 | |
| SCHEMBL14588475 | 0.73 | FNTA (0.62) | FNTAFNTBCNR1CYP3A4 | |
| SCHEMBL8171779 | 0.73 | FNTA (0.55) | FNTAFNTB | |
| SCHEMBL1538260 | 0.73 | FNTA (0.56) | FNTAFNTBKMT2ACYP3A4 | |
| SCHEMBL30419724 | 0.73 | FNTA (0.56) | FNTAFNTBKMT2ACYP3A4 | |
| SCHEMBL5655102 | 0.70 | FNTA (1.00) | FNTAFNTBCNR1CYP3A4 | |
| SCHEMBL11955322 | 0.69 | FNTA (0.60) | FNTAFNTBCYP3A4 | |
| SCHEMBL6170916 | 0.69 | FNTA (0.55) | FNTAFNTBKMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173040-B2 | Farnesyl transferase inhibiting 6-[(substituted phenyl)methyl]-quinoline and quinazoline derinazoline derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-02-06 | — | — | US | disclosed |
| US-7173040-B2 | Farnesyl transferase inhibiting 6-[(substituted phenyl)methyl]-quinoline and quinazoline derinazoline derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-02-06 | — | — | US | disclosed |