Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.81 |
| ▸ | FNTB | P49356 | 11/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165515 | 0.92 | FNTA (0.79) | FNTAFNTBCYP3A4 | |
| SCHEMBL6165521 | 0.92 | FNTA (0.79) | FNTAFNTBCYP3A4 | |
| SCHEMBL5656502 | 0.92 | FNTA (0.87) | FNTAFNTBCYP3A4 | |
| SCHEMBL5655379 | 0.92 | FNTA (0.78) | FNTAFNTBCYP3A4 | |
| SCHEMBL5655374 | 0.92 | FNTA (0.78) | FNTAFNTBCYP3A4 | |
| SCHEMBL13928075 | 0.90 | FNTA (1.00) | FNTAFNTBCYP3A4 | |
| SCHEMBL1682772 | 0.90 | FNTA (1.00) | FNTAFNTBCYP3A4 | |
| Hydrochloric Acid SCHEMBL6435591 | 0.89 | FNTA (0.98) | FNTAFNTBCYP3A4 | |
| SCHEMBL6010387 | 0.89 | FNTA (0.91) | FNTAFNTBCYP3A4 | |
| SCHEMBL5654543 | 0.88 | FNTA (0.96) | FNTAFNTBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173040-B2 | Farnesyl transferase inhibiting 6-[(substituted phenyl)methyl]-quinoline and quinazoline derinazoline derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-02-06 | — | — | US | disclosed |
| US-7173040-B2 | Farnesyl transferase inhibiting 6-[(substituted phenyl)methyl]-quinoline and quinazoline derinazoline derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-02-06 | — | — | US | disclosed |