Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.79 |
| ▸ | FNTB | P49356 | 10/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.57 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165521 | 1.00 | FNTA (0.79) | FNTAFNTBCYP3A4RORC | |
| SCHEMBL14588488 | 0.92 | FNTA (0.81) | FNTAFNTBCYP3A4 | |
| SCHEMBL6163431 | 0.92 | FNTA (0.75) | FNTAFNTBCYP3A4RORC | |
| SCHEMBL6165578 | 0.91 | FNTA (0.82) | FNTAFNTBCYP3A4RORC | |
| SCHEMBL7044225 | 0.90 | FNTA (0.81) | FNTAFNTBCYP3A4RORC | |
| SCHEMBL6161628 | 0.90 | FNTA (0.73) | FNTAFNTBCYP3A4RORC | |
| SCHEMBL6163870 | 0.90 | FNTA (0.72) | FNTAFNTBCYP3A4RORC | |
| SCHEMBL1682772 | 0.88 | FNTA (1.00) | FNTAFNTBCYP3A4 | |
| SCHEMBL13928075 | 0.88 | FNTA (1.00) | FNTAFNTBCYP3A4 | |
| SCHEMBL7672698 | 0.88 | FNTA (0.69) | FNTAFNTBCYP3A4RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107962-B1 | QUINOLIN-2-ONE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PROD INC (US) | 2005-02-23 | — | — | EP | disclosed |
| US-6495564-B1 | SUCH AS 3-(6-((4-CHLORO-PHENYL)-HYDROXY-(3-METHYL-3H-IMIDAZOL-4-YL)-METHYL)-1-METHYL-2-OXO-1,2-DIHYDRO-QUINOLIN-4-YL)-BENZALDEHYDE O-METHYL-OXIME; INHIBITING ABNORMAL CELL GROWTH | PFIZER INC. | 2002-12-17 | — | — | US | disclosed |