Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 19/20 | 0.61 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27769601 | 0.85 | CTSA (0.61) | CTSA | |
| SCHEMBL27911957 | 0.82 | CTSA (0.59) | CTSA | |
| SCHEMBL9839153 | 0.82 | CTSA (0.62) | CTSA | |
| SCHEMBL6538454 | 0.82 | CTSA (0.49) | CTSA | |
| SCHEMBL8145856 | 0.79 | HTR2A (0.52) | CTSA | |
| SCHEMBL17294112 | 0.79 | HTR2A (0.52) | CTSA | |
| SCHEMBL25420392 | 0.78 | CTSA (0.45) | CTSAHRH2HRH4 | |
| SCHEMBL1669626 | 0.77 | CTSA (0.52) | CTSA | |
| SCHEMBL17284357 | 0.76 | CTSA (1.00) | CTSA | |
| SCHEMBL1383474 | 0.76 | CYP2C19 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483280-A1 | NEW AMINOACID DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS INHIBITORS OF ONCOGENIC SIGNALS BY THE MET FAMILY | Université d'Aix-Marseille (FR) | 2012-08-08 | — | — | EP | claimed |
| EP-2305688-A1 | Novel aminoacids derivatives, their process of preparation and their therapeutical uses as MET inhibitors | Université de la Méditerranée - Aix-Marseille II (FR) | 2011-04-06 | — | — | EP | claimed |
| WO-2011036303-A1 | NEW AMINOACID DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS INHIBITORS OF ONCOGENIC SIGNALS BY THE MET FAMILY | UNIVERSITE DE LA MEDITERRANEE AIX-MARSEILLE II (FR) | 2011-03-31 | — | — | WO | claimed |
| EP-2483280-A1 | NEW AMINOACID DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS INHIBITORS OF ONCOGENIC SIGNALS BY THE MET FAMILY | Université d'Aix-Marseille (FR) | 2012-08-08 | — | — | EP | disclosed |
| EP-2305688-A1 | Novel aminoacids derivatives, their process of preparation and their therapeutical uses as MET inhibitors | Université de la Méditerranée - Aix-Marseille II (FR) | 2011-04-06 | — | — | EP | disclosed |
| WO-2011036303-A1 | NEW AMINOACID DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS INHIBITORS OF ONCOGENIC SIGNALS BY THE MET FAMILY | UNIVERSITE DE LA MEDITERRANEE AIX-MARSEILLE II (FR) | 2011-03-31 | — | — | WO | disclosed |