Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | EDNRB | P24530 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MC4R | P32245 | 1/20 | 0.52 |
| ▸ | MC3R | P41968 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.50 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5011439 | 0.98 | CYP2C19 (0.65) | CYP2C19CYP2D6CYP1A2PKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29096814 | 0.98 | CYP2C19 (0.65) | CYP2C19CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL29031805 | 0.90 | CYP2C19 (0.57) | CYP2C19CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL2203786 | 0.88 | CYP2C19 (0.56) | CYP2C19CYP2D6CYP1A2PKMSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL29921749 | 0.88 | CYP2C19 (0.56) | CYP2C19CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL3911220 | 0.88 | CYP2C19 (0.67) | CYP2C19CYP2D6CYP1A2PKMSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6378333 | 0.88 | CYP2C19 (0.56) | CYP2C19CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL28682706 | 0.85 | CYP2C19 (0.53) | CYP2C19CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL9105247 | 0.84 | ALDH1A1 (0.63) | CYP2C19CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL4438449 | 0.84 | CACNA1A (0.56) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960030-A | Preparation method of 3-subunit oxindole derivative | 湖北工业大学 | 2023-04-14 | — | — | CN | claimed |
| CN-109438277-A | Oximido naphthoquinone compound and its preparation method and application | 普济生物科技（台州）有限公司 | 2019-03-08 | — | — | CN | claimed |
| EP-2457895-A1 | Tetrapeptide analogs | Idun Pharmaceuticals, Inc. (US) | 2012-05-30 | — | — | EP | claimed |
| JP-4838934-B2 | — | — | 2011-12-14 | — | — | JP | claimed |
| US-7829568-B2 | Substituted 5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-ylamine compounds and their use for producing drugs | GRUENENTHAL GMBH (DE) | 2010-11-09 | — | — | US | claimed |
| US-20100279936-A1 | SUBSTITUTED ACETYLENIC COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-11-04 | — | — | US | claimed |
| US-20100190688-A1 | Tetrapeptide analogs | IDUN PHARMACEUTICALS, INC. | 2010-07-29 | — | — | US | claimed |
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |
| US-RE40851-E1 | 3,3-diphenylpropylamines, their use and preparation | PFIZER HEALTH AB (SE) | 2009-07-14 | — | — | US | claimed |
| EP-1869038-B1 | SUBSTITUTED 5,6,7,8-TETRAHYDRO-IMIDAZO[1,2-A]PYRIDIN-2-YLAMINE COMPOUNDS AND THEIR USE FOR PRODUCING DRUGS | GRUENENTHAL GMBH (DE) | 2009-07-08 | — | — | EP | claimed |
| EP-0667852-B1 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-04-08 | — | — | EP | claimed |
| JP-2664503-B2 | — | — | 1997-10-15 | — | — | JP | claimed |
| US-5559269-A | ANTICHOLINERGIC AGENTS | PHARMACIA AB (SE) | 1996-09-24 | — | — | US | claimed |
| EP-0667852-A1 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1995-08-23 | — | — | EP | claimed |
| WO-1994011337-A9 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | — | 1995-07-06 | — | — | WO | claimed |
| WO-1994011337-A1 | NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION | PHARMACIA AB (SE) | 1994-05-26 | — | — | WO | claimed |
| EP-0325571-B1 | NEW AMINES, THEIR USE AND PREPARATION | Kabi Pharmacia AB (SE) | 1991-08-07 | — | — | EP | claimed |
| EP-0354234-A1 | NEW AMINES, THEIR USE AND PREPARATION | KabiVitrum AB (SE) | 1990-02-14 | — | — | EP | claimed |
| WO-1989006644-A1 | NEW AMINES, THEIR USE AND PREPARATION | KABIVITRUM AB (SE) | 1989-07-27 | — | — | WO | claimed |
| EP-0325571-A1 | New amines, their use and preparation | Kabi Pharmacia AB (SE) | 1989-07-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279936-A1 | SUBSTITUTED ACETYLENIC COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES | C1R, C3AR1, PTH1R | CYP2C19 494/4885CYP2D6 307/4885CYP1A2 1729/4885 |
| US-20100190688-A1 | Tetrapeptide analogs | TP53, PCNA, HRAS | CYP2C19 4851/4885CYP2D6 4790/4885CYP1A2 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.