SCHEMBL145904

SCHEMBL145904

CCN1C(=O)CC(=O)NC1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.49
MEN1 O00255 11/20 0.49
KMT2A Q03164 11/20 0.49
ALDH1A1 P00352 5/20 0.49
HSD17B10 Q99714 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
POLB P06746 2/20 0.46
APEX1 P27695 2/20 0.46
RECQL P46063 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
PKM P14618 1/20 0.46
CYP2C19 P33261 1/20 0.46
PSMD14 O00487 1/20 0.46
MMP2 P08253 1/20 0.46
DNMT1 P26358 1/20 0.46
PTPN7 P35236 1/20 0.46
HBB P68871 1/20 0.46
KDM4C Q9H3R0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7864240 0.98 MAPT (0.47) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL27918051 0.84 MAPT (0.47) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL3294487 0.83 MAPT (0.51) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL12851529 0.81 MEN1 (0.56) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL11167414 0.80 MAPT (0.56) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL2161839 0.79 MAPT (0.49) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL28151841 0.78 MAPT (0.47) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL9885883 0.78 MAPT (0.46) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL14185382 0.77 MEN1 (0.46) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL2376601 0.77 MAPT (0.45) MAPTMEN1KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3830160-B1 METHODS FOR REDUCING ALDEHYDE EMISSIONS IN POLYURETHANE FOAMS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-06-25 EP claimed
US-11479650-B2 Methods for reducing aldehyde emissions in polyurethane foams DOW GLOBAL TECHNOLOGIES LLC (US) 2022-10-25 US claimed
CN-110446731-B Polyurethane foams with low aldehyde emission levels 陶氏环球技术有限责任公司 2022-06-07 CN claimed
US-20210292508-A1 METHODS FOR REDUCING ALDEHYDE EMISSIONS IN POLYURETHANE FOAMS DOW CHEMICAL JAPAN LIMITED (JP) 2021-09-23 US claimed
US-20210189054-A1 METHODS FOR REDUCING ALDEHYDE EMISSIONS IN POLYURETHANE FOAMS DOW GLOBAL TECHNOLOGIES LLC 2021-06-24 US claimed
US-20200031983-A1 POLYURETHANES HAVING LOW LEVELS OF ALDEHYDE EMISSIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-01-30 US claimed
CN-110446731-A Polyurethane foam with low aldehyde emission level DOW GLOBAL TECHNOLOGIES LLC 2019-11-12 CN claimed
EP-3830160-B1 METHODS FOR REDUCING ALDEHYDE EMISSIONS IN POLYURETHANE FOAMS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-06-25 EP disclosed
US-20240132449-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF 1CBIO, INC. 2024-04-25 US disclosed
WO-2024050370-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF 1CBIO, INC. (US) 2024-03-07 WO disclosed
US-11820855-B2 Methods for reducing aldehyde emissions in polyurethane foams DOW GLOBAL TECHNOLOGIES LLC 2023-11-21 US disclosed
CN-116583560-A Rubber composition for hot air crosslinking, crosslinked rubber, and method for producing crosslinked rubber 日油株式会社 2023-08-11 CN disclosed
CN-112638975-B Method for reducing aldehyde emissions in polyurethane foams 陶氏环球技术有限责任公司 2023-05-16 CN disclosed
EP-0111919-A2 Multicolor photographic elements containing silver iodide grains EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-06-27 EP disclosed
US-4439520-A Sensitized high aspect ratio silver halide emulsions and photographic elements EASTMAN KODAK COMPANY (US) 1984-03-27 US disclosed
US-4418142-A ALDEHYDE SCAVANGERS AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1983-11-29 US disclosed
US-4382983-A PARTIALLY HYDROLYZED SILOXANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-05-10 US disclosed
US-4239762-A INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-12-16 US disclosed
US-4062836-A YELLOW CIBA-GEIGY CORPORATION (US) 1977-12-13 US disclosed
US-4036823-A Barbituric acid antigenic conjugates, their preparation, antibodies and use BIOLOGICAL DEVELOPMENTS, INC. (US) 1977-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132449-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF PARP1, PARP11, PARP12 MAPT 4689/4885MEN1 2494/4885KMT2A 1465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.