SCHEMBL7864240

SCHEMBL7864240

CCN1C(=O)CC(=O)NC1=O.[Na]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.47
MEN1 O00255 11/20 0.47
KMT2A Q03164 11/20 0.47
ALDH1A1 P00352 5/20 0.47
HSD17B10 Q99714 4/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
POLB P06746 2/20 0.45
APEX1 P27695 2/20 0.45
RECQL P46063 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
PKM P14618 1/20 0.45
CYP2C19 P33261 1/20 0.45
PSMD14 O00487 1/20 0.45
MMP2 P08253 1/20 0.45
DNMT1 P26358 1/20 0.45
PTPN7 P35236 1/20 0.45
HBB P68871 1/20 0.45
KDM4C Q9H3R0 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145904 0.98 MAPT (0.49) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL27918051 0.82 MAPT (0.47) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL3294487 0.81 MAPT (0.51) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL12851529 0.79 MEN1 (0.56) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL11167414 0.79 MAPT (0.56) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL2161839 0.78 MAPT (0.49) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL9885883 0.76 MAPT (0.46) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL28151841 0.76 MAPT (0.47) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL14185382 0.76 MEN1 (0.46) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL2376601 0.75 MAPT (0.45) MAPTMEN1KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0700399-B1 36-DERIVATIVES OF RIFAMYCINS AND THEIR USE AS ANTIMICROBIAL AGENTS LEPETIT SPA (IT) 2001-10-04 EP disclosed
US-5786350-A CONDENSATION; HYDROLYSIS; DEPROTECTING GRUPPO LEPETIT S.P.A. (IT) 1998-07-28 US disclosed
EP-0700399-A1 36-DERIVATIVES OF RIFAMYCINS AND THEIR USE AS ANTIMICROBIAL AGENTS GRUPPO LEPETIT S.P.A. (IT) 1996-03-13 EP disclosed
WO-1994028002-A1 36-DERIVATIVES OF RIFAMYCINS AND THEIR USE AS ANTIMICROBIAL AGENTS GRUPPO LEPETIT S.P.A. (IT) 1994-12-08 WO disclosed