Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 9/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14590947 | 0.84 | ADORA1 (0.48) | ADORA1ADORA2AALDH1A1TSHR | |
| SCHEMBL14590949 | 0.84 | ADORA1 (0.48) | ADORA1ADORA2AALDH1A1TSHR | |
| SCHEMBL4550705 | 0.84 | ADORA1 (0.48) | ADORA1ADORA2AALDH1A1TSHR | |
| SCHEMBL4550706 | 0.78 | ADORA1 (0.51) | ADORA1ADORA2AHPGDALDH1A1KDM4E | |
| SCHEMBL4259479 | 0.66 | ADORA1 (0.77) | ADORA1ADORA2AALDH1A1KDM4ETSHR | |
| SCHEMBL21664313 | 0.66 | GBA1 (0.57) | HSD17B10GBA1MAPTTSHR | |
| SCHEMBL15426758 | 0.66 | ADORA1 (0.77) | ADORA1ADORA2AHPGDSMN1; SMN2 | |
| SCHEMBL11184213 | 0.65 | GBA1 (0.64) | ALDH1A1HSD17B10GBA1MAPTTP53 | |
| SCHEMBL13649848 | 0.65 | ADORA1 (0.60) | ADORA1ADORA2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8353560 | 0.64 | ADORA1 (0.66) | ADORA1ADORA2AHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160890-B2 | Compounds specific to adenosine A3 receptor and uses thereof | OSI PHARMACEUTICALS, INC. (US) | 2007-01-09 | — | — | US | disclosed |