Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 7/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.48 |
| ▸ | BTK | Q06187 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.41 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14590947 | 1.00 | ADORA1 (0.48) | ADORA1ADORA2ABTKALDH1A1TSHR | |
| SCHEMBL4550705 | 1.00 | ADORA1 (0.48) | ADORA1ADORA2ABTKALDH1A1TSHR | |
| SCHEMBL4550706 | 0.88 | ADORA1 (0.51) | ADORA1ADORA2AALDH1A1TSHRSMPD3 | |
| SCHEMBL14591091 | 0.84 | ADORA1 (0.46) | ADORA1ADORA2AALDH1A1TSHR | |
| SCHEMBL15426758 | 0.76 | ADORA1 (0.77) | ADORA1ADORA2ABTK | |
| SCHEMBL17628114 | 0.69 | PRKDC (0.51) | BTKSMPD3KIF11 | |
| SCHEMBL17628115 | 0.69 | PRKDC (0.51) | BTKSMPD3KIF11 | |
| SCHEMBL17628281 | 0.69 | OPRM1 (0.44) | BTKPPARDPPARASMPD3IRAK4 | |
| SCHEMBL17628278 | 0.69 | OPRM1 (0.44) | BTKPPARDPPARASMPD3IRAK4 | |
| SCHEMBL21664227 | 0.66 | MAPT (0.58) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160890-B2 | Compounds specific to adenosine A3 receptor and uses thereof | OSI PHARMACEUTICALS, INC. (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160890-B2 | Compounds specific to adenosine A3 receptor and uses thereof | OSI PHARMACEUTICALS, INC. (US) | 2007-01-09 | — | — | US | disclosed |