Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 4/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14591892 | 0.88 | MAPT (0.44) | ITGA4ITGB1MAPTMEN1TP53 | |
| SCHEMBL2429149 | 0.87 | ITGB1 (0.55) | ITGA4ITGB1MAPTMEN1TP53 | |
| SCHEMBL12327294 | 0.87 | ITGB1 (0.53) | ITGA4ITGB1MAPTMEN1TP53 | |
| SCHEMBL14591890 | 0.84 | ITGB1 (0.54) | ITGA4ITGB1MAPTMEN1TP53 | |
| SCHEMBL14591851 | 0.83 | CYP1A2 (0.45) | ITGA4ITGB1MAPTMEN1TP53 | |
| SCHEMBL14591839 | 0.83 | RAB9A (0.52) | ITGA4MAPTMEN1KMT2ARAB9A | |
| SCHEMBL91540 | 0.80 | RAB9A (0.55) | MAPTMEN1TP53TSHRKMT2A | |
| SCHEMBL14591885 | 0.80 | MAPT (0.52) | ITGA4ITGB1MAPTTP53 | |
| SCHEMBL2429653 | 0.79 | AKR1B1 (0.46) | ITGA4ITGB1MAPTMEN1TP53 | |
| SCHEMBL14591866 | 0.79 | KDM4E (0.51) | ITGA4TSHRITGB7HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |