Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 20/20 | 0.87 |
| ▸ | ITGB1 | P05556 | 17/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14592130 | 0.93 | ITGA4 (0.77) | ITGA4ITGB1 | |
| SCHEMBL14592229 | 0.93 | ITGB1 (1.00) | ITGA4ITGB1 | |
| SCHEMBL14592250 | 0.93 | ITGB1 (0.87) | ITGA4ITGB1 | |
| SCHEMBL14592231 | 0.92 | ITGA4 (0.75) | ITGA4ITGB1 | |
| SCHEMBL14592245 | 0.91 | ITGB1 (0.88) | ITGA4ITGB1 | |
| SCHEMBL14592240 | 0.90 | ITGA4 (0.89) | ITGA4ITGB1 | |
| SCHEMBL14592252 | 0.89 | ITGB1 (0.69) | ITGA4ITGB1 | |
| SCHEMBL14592234 | 0.89 | ITGA4 (0.69) | ITGA4ITGB1 | |
| SCHEMBL14592113 | 0.88 | ITGA4 (0.88) | ITGA4ITGB1 | |
| SCHEMBL14592131 | 0.88 | ITGA4 (0.77) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |